Research on Molecular Mechanism of Non-small Cell Lung Cancer ( NSCLC) Based on Bioinformatics 非小细胞肺癌发生分子机制的生物信息学研究
The results could provide a molecular explanation for the continued increased risk of lung cancer and other pulmonary ailments among former smokers. 该结果可能为戒烟者患肺癌及其他肺病风险持续增加提供一种分子水平的解释。
The Studies on Molecular Cytogenetic Alterations in Human Lung Carcinomas 人肺癌分子细胞遗传学异常改变的研究
Application of SELDI-TOF-Ms technology in research of molecular markers of lung cancer Establishment of serum protein pattern model for diagnosing nasopharyngeal carcinoma using surface enhanced laser desorption/ ionization time-of-flight mass spectrometry 蛋白质指纹图谱技术在肺癌分子标志物研究中的应用应用SELDI-TOF-MS技术建立鼻咽癌诊断中的血清蛋白质指纹图谱模型
Results of this study, which were presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer, support ongoing Phase III studies of ASA404 in NSCLC. 在肺癌分子起源AACR-IASLC联席会议上发布的这项研究结果支持目前正在进行的ASA404在NSCLC中的III期研究。
An Experimental Study of the Fungi of Huai Ers Effect on the Antiangiogenesis and Its Molecular Mechanisms in Human Lung Cancer; 目的探讨槐耳清膏对人脐静脉内皮细胞体外构建新生血管的影响及其初步机制。
Objective: To investigate the effect of skeletal muscle ischemia/ reperfusion injury on the expression of intercellular adhesive molecular ( ICAM)-1 in lung. 目的:探讨骨骼肌缺血再灌注(I/R)对肺细胞间黏附分子1(ICAM1)表达的影响。
In vivo molecular imaging of GFP labeled Lewis lung cancer in mice model 小鼠Lewis肺癌移植瘤模型活体分子成像研究
Clinical-Pathological Study on Nodal Molecular Staging of Non-Small-Cell Lung Cancer 非小细胞肺癌淋巴结分子分期的临床病理研究
Epidermal growth factor receptor family and molecular targeting therapy of lung cancer 上皮生长因子受体家族与肺癌的分子靶向治疗
Conclusion The model of malignant transformation of BEAS-2B cells induced by NNK could be created successfully and provided for investigating the molecular biological mechanism of lung cancer, especially smoking-related cases. 结论:NNK能成功诱发人支气管上皮细胞(BEAS-2B)细胞恶性转化,为进一步探讨肺癌发生机制、尤其是吸烟致肺癌发生机制提供了理想模型。
Molecular cloning of a novel human lung cancer associated antigen cDNA 人肺癌相关抗原的基因克隆
Association of molecular biology of lung cancers and their metastasis and prognosis 肺癌分子生物学特性与转移和预后的关系
Molecular biology techniques and progress of screening lung cancer through sputum sample 基因点突变检测肺癌分子生物学筛查的方法及进展
Lung cancer is a gene disease. With the progress of molecular biology and molecular oncology, gene therapy for lung cancer becomes a prospective therapy in the field of medical studies. 肺癌是一种基因病,随着现代分子肿瘤学的发展,肺癌的基因治疗成为继手术、放、化疗后最具前景的治疗手段。
The Research on Development of the Molecular Staging of Lung Cancer 肺癌的分子分期相关研究进展
Conclusion The amount of bcl 2 mRNA and Bax protein increased obviously in lung cancer, bcl 2 and Bax gene can become molecular markers of lung cancer. 结论bcl-2、Bax蛋白在肺癌中的表达率较高,bcl-2、Bax可能会成为肺癌的重要分子标志物。
Abnormalities of Molecular Biology in Premalignant Lung Lesions 肺癌癌前病变中的分子生物学异常事件
Study on molecular pathology in non-small cell lung cancer in Shanghai 非小细胞肺癌分子病理学的研究
Research Advance on Molecular and Cellular Biology of Small Cell Lung Cancer 小细胞肺癌分子细胞生物学的研究进展
Objective To investigate gene diagnosis of micrometastasis in lymph nodes in patients with non small cell lung cancer ( NSCLC) and the feasibility of mucin 1 ( MUC1) mRNA and cytokeratin 19 ( CK19) mRNA as molecular marker to detect micrometastasis of lung cancer. 目的探讨非小细胞肺癌(NSCLC)淋巴结微转移的基因诊断方法,并分析CK19mRNA、MUC1mRNA作为肺癌微转移检测分子标志物的可行性。
Therefore, to cure lung adenocarcinoma is the key to reduce lung cancer mortality rate. However, no effective treatments for lung adenocarcinoma could be available now, because the molecular mechanisms underlying lung adenocarcinoma apoptosis have not been clarified. 因此,治疗肺腺癌对于降低肺癌死亡率甚为关键。然而迄今为止,肺腺癌细胞凋亡分子机制尚未搞清,阻碍了肺腺癌的有效治疗。
Molecular biology studies have shown that lung cancer is a complexity of multi-stage biological process with multi-factors being involved, including activation of oncogene and inactivation of tumor suppressor gene. 分子生物学研究表明,肺癌的发生是一个多因素共同参与、多阶段的复杂生物学过程,与癌基因激活、抑癌基因失活密切相关。
Researchers in NSCLC patients in somatic cells determine the epidermal growth factor receptor tyrosine kinase domain of somatic protein-altering mutations. The target molecular target therapy about EGFR in non-small cell lung cancer treatment came out gradually. 研究人员在非小细胞肺癌病人身上确定了在体细胞EGFR酪氨酸激酶的突变,以EGFR为靶点的分子靶向治疗在NSCLC的治疗中日渐突出。
Conclusion: Bronchial lavages supernatants are helpful for molecular diagnosis of lung cancer. Hypermethylation of anti-oncogene is a useful marker for diagnosis of lung cancer. 结论支气管灌洗液上清对肺癌分子生物学诊断有一定帮助,抑癌基因的过甲基化可作为肺癌诊断有用的标记。
In recent years, with the progression of medical molecular biology, targeted therapy aimed at the molecular events of lung cancer has been a focus of research. 近年来,随着医学分子生物学技术和理论的进展,针对肺癌发病的分子事件的靶向治疗备受关注。
Besides the traditional treatment, such as operation, radiotherapy and chemotherapeutics, molecular targeting therapy of lung cancer has been developed rapidly in recent years, but it is still the second-line treatment to lung cancer. 除了手术、放疗及传统化疗药物之外,更多研究开始关注于分子靶向药物的开发,但由于这些药物疗效的不稳定性,般仅作为肺癌治疗的二线药物。
The epidermal growth factor receptor kinase inhibitors ( EGFR-TKI) play an important role in molecular target therapy of lung cancer. 以表皮生长因子受体酪氨酸激酶抑制剂(EGFR-TKI)为基础的分子靶向药物治疗在肺癌的治疗中发挥着重要作用,成为国内外研究的热点。